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    InVivo Prime Pro Anti-Mouse PD-1 Recombinant mAb [RMP1-14]

    Application:

    In vivo

    Species reactivity:

    Mouse

    Host species:

    Rat

    InVivo Prime Pro Anti-Mouse PD-1 Recombinant mAb [RMP1-14],NeoMab,FM0002P
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    One-click copy of information

    Instruction manual

    List price:

    ¥ 3120

    Catalog:

    FM0002P

    • Specification
      • 5mg
      • 25mg
      • 50mg
      • 100mg
      • Customized specifications (specific negotiation)
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    隐藏域元素占位

    • Product Description
    • Composition
    • Precautions
    • Product overview:

      Product name: InVivo Prime Pro Anti-Mouse PD-1 Recombinant mAb [RMP1-14]
      Antibody type: Monoclonal
      Validated application: in vivo
      Host: Rat
      Species reactivity: Mouse
      Clone number: 10F.9G2
      Isotype: Rat IgG2b.

       

       

      Background of the target:

      PD-1 (also known as CD279) is an immune checkpoint receptor that negatively regulates immune responses and helps

      maintain self-tolerance. Multiple immune cells express PD-1, including T cells, B cells, macrophages and dendritic cells. Binding of PD-1 to PD-L1/PD-L2 will lead to the inhibition of T-cell activation and function. Immunotherapy strategies that inhibit the binding of PD-1 and PD-L1 have shown great efficacy in cancer treatment.

      Location: Cell membrane

      NCBI Gene ID: 18566

      SwissProt: Q02242

      Alternate Names: Programmed Death-1, Ly101, Pdc1, CD279

       

       

       

       

      Properties

       

      Form Liquid
      Formulation The antibody is formulated in PBS (pH 7.2) without carrier protein and preservatives. Sterile by 0.22 µm filtration.
      Purity >95%. Determined by SDS-PAGE.
      Endotoxin < 0.001 EU/μg. Determined by the LAL assay.
      Shipping 2-8°C.
      Storage The product should be stored under sterile conditions at 2-8°C.

       

       

       

       

      Application dilutions

      Flow Cytometry 0.2 μg/mL

       

       

       

       

      Application data

       

       

       

       

    • Storage: Store at 2–8°C, protected from light. Transport with ice packs.

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